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1 OMIM reference -
4 associated genes
14 signs/symptoms
COMMON GENES: 1
COMMON SIGNS: 1
2 associated genes
12 signs/symptoms
Follicular lymphoma
Bullous pemphigoid

BCL2 HLA-DQB1
BCL6 HLA-DRB1
HLA-DRB1
IGH


COMMON
GENES
HLA-DRB1



Citations in the biomedical literature:


Follicular lymphoma
BCL2 BCL6 HLA-DRB1 IGH
Bullous pemphigoid
HLA-DQB1



Follicular lymphoma
Bullous pemphigoid

Classification (Orphanet):
- Rare hematologic disease
- Rare oncologic disease
Classification (Orphanet):
- Rare skin disease

Classification (ICD10):
- Neoplasms -
Classification (ICD10):
- Diseases of the skin and subcutaneous tissue -

Epidemiological data:
Class of prevalence: 1-5 / 10 000
Average age onset: adulthood
Average age of death: adult
Type of inheritance: multigenic/multifactorial
Epidemiological data:
(no data available)

External references:
1 OMIM reference -
1 MeSH reference: D008224
External references:
No OMIM references
1 MeSH reference: D010391


COMMON
SIGNS
- Weight loss / loss of appetite / break in weight curve / general health alteration


Follicular lymphoma
Bullous pemphigoid

Very frequent
- Fever / chilling
- Hematologic / blood / lymphatic cancer
- Hyperhidrosis / increased sweating
- Lymphadenopathy / polyadenopathies

Frequent
- Asthenia / fatigue / weakness
- Mediastinal / hilar adenopathies
- Splenomegaly

Occasional
- Abnormal pleura / hydrothorax / pleuresia / pleural effusion / chylothorax
- Anomalies of skin, subcutaneous tissue and mucosae
- Bone marrow / medullar infiltration
- Lymphedema
- Meningitis / meningeal syndrome
- Structural anomaly of the peritoneum


Very frequent
- Autoimmunity / autoimmune reaction / autoantibodies
- Diabetes mellitus
- Eczema
- Enanthema / aphtosa / aphta / leukoplakia
- Erythema / erythematous lesions / erythroderma / polymorphous erythema
- Immunodeficiency / increased susceptibility to infections / recurrent infections
- Macules
- Negative Nikolski's sign
- Urticaria
- Vesicles / bullous / exsudative lesions / bullous / cutaneous / mucosal detachment

Frequent
- Psoriasis